IUT increases long bone strength and cortical thickness. (A) Mechanical properties (3-point bending test) of ulna and tibia in 4-week-old mice that received transplants (OIM + IUT; n = 8) and oim mice that did not receive transplants (OIM; n = 4). Yield force (N), ultimate force (N), stiffness (N/mm), and ultimate force (N). *P < .05. (B) Femoral cortical thickness in 4-week-old (n = 6), 8-week-old (n = 4), and 12-week-old (n = 3) OIM + IUT and OIM mice (n = 7, 4, and 4, respectively). Cx indicates cortex; and BM, bone marrow. Bars on graphs are means ± SE.