Human B cells transfected with p.DOM-WT1.37 present the WT1.37/HLA complex to, and are lysed by, WT1.37-specific T cells. The VAL follicular lymphoma (HLA-A*0201⁺WT1⁻) cell line was transfected with p.DOM-WT1.37 or with control plasmids p.DOM or p.EGFP. Twenty-four hours later, transfectants were tested for their susceptibility to lysis by human WT1.37-specific CTLs. Data shown are representative of 3 experiments performed.