American Society of Hematology

Figure 5

rs2775139 and SLC25A37. rs2775139 is variable in both CEU and YRI cell lines. In the CEU cell lines, genotype is associated with both (A) AUC (P = 8 × 10−6) and (B) expression of SLC25A37 (P = 1 × 10−6). Among the YRI cell lines, all genotypes demonstrate similar (A) AUC and (B) SLC25A37 expression. (C) Expression of SLC25A37 and AUC was significantly correlated in the CEU population (r2 = 0.169, P = 7 × 10−4). (D) This association was validated in an independent set of CEU cell lines in which AUC significantly correlated with expression of SLC25A37 (r2 = 0.0817, P = .05).

rs2775139 and SLC25A37. rs2775139 is variable in both CEU and YRI cell lines. In the CEU cell lines, genotype is associated with both (A) AUC (P = 8 × 10⁻⁶) and (B) expression of SLC25A37 (P = 1 × 10⁻⁶). Among the YRI cell lines, all genotypes demonstrate similar (A) AUC and (B) SLC25A37 expression. (C) Expression of SLC25A37 and AUC was significantly correlated in the CEU population (r² = 0.169, P = 7 × 10⁻⁴). (D) This association was validated in an independent set of CEU cell lines in which AUC significantly correlated with expression of SLC25A37 (r² = 0.0817, P = .05).

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