Schematic representation of lentiviral vectors encoding full-length murine Adamts13 and eGFP reporter genes. Murine full-length ADAMTS13 (encoding amino acid residues 1-1426, mAdamts13) and enhanced green fluorescent protein (eGFP) were cloned into a self-inactivating HIV-1–based vector ZHK to form ZHK-MND-eGFP-Tav3-mAdamts13 (mA13) and ZHK-MND-GFP (GFP). These vectors contain a modified myeloid proliferative sarcoma virus (MND) promoter, an eGFP reporter gene, and Tav sequence. The rev response element (RRE) and the Woodchuck hepatitis virus posttranscriptional regulatory element (WPRE), enhancing expression of the transgene, are indicated above the schematic vector structures.