Figure 4
Figure 4. NOD/SCID-repopulating cells (SRCs) are enriched within the CD34+BB9+ subpopulation. Groups of mice received a transplant of CD34+ (▲), CD34+BB9+ (●), or CD34+BB9− cells (○) at the doses shown. Shown are the levels of human engraftment assessed by flow cytometric analysis of the bone marrow at week 10 after engraftment using anti-hCD45. The mean percentage of hCD45 in each group is indicated.

NOD/SCID-repopulating cells (SRCs) are enriched within the CD34+BB9+ subpopulation. Groups of mice received a transplant of CD34+ (▲), CD34+BB9+ (●), or CD34+BB9 cells (○) at the doses shown. Shown are the levels of human engraftment assessed by flow cytometric analysis of the bone marrow at week 10 after engraftment using anti-hCD45. The mean percentage of hCD45 in each group is indicated.

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