Leukemic cells of mice/D171N with high expression of Evi1 invaded into liver and kidney. (A) Spleen from morbid mice/D171N (left) and from normal mice (right). Histopathologic findings of (B) spleen, (D) liver, and (F) kidney infiltrated with leukemic cells from mice/D171N, stained with H&E. Histopathologic findings of (C) spleen, (E) liver, and (G) kidney from normal mice, stained with H&E. (H) Mice/D171N showed a high percentage of blasts in bone marrow. Cytospin preparations of BM cells from (H) mice/D171N and (I) normal mice, stained with Giemsa. (BX51 microscope, DP12 camera module; objective lens, UPlanFl; magnification, ×200 (B-E); ×100 (F,G); and ×1000 (H,I).