Figure 2
Platelet-derived microparticles generated by heparin-induced thrombocytopenia serum. Platelets and microparticles were identified using fluorescence (FL1, FITC-antiGPIb3) and size (FSC, forward scatter) characteristics. The platelets had been incubated with heparin-induced thrombocytopenia serum in the presence of 0, 0.1, 0.3, or 100 U/mL heparin. The microparticles (inset box) were generated in the presence of 0.1 and 0.3 U/mL heparin, but not at 0 or 100 U/mL heparin. Results of the representative experiment are shown. Adapted from Warkentin et al45 with permission.
