Proposed model for L- and P-selectin–mediated, mucin-induced activation and aggregation of platelets. Yellow circle labeled with L indicates L-selectin ligands on mucins. Blue boxes labeled with P indicate P-selectin ligands, including carcinoma mucins and PSGL-1 expressed on leukocytes. L-sel indicates L-selectin; P-sel, P-selectin. Reproduced from Wahrenbrock et al¹  with permission of the publishers.