In a novel mouse model of MDS/AML, retroviral transduction is hypothesized to create two hits (expression of the mutant AML1D171N allele and activation of Evi1 via insertional mutagenesis) that converge on AML1 function.
In a novel mouse model of MDS/AML, retroviral transduction is hypothesized to create two hits (expression of the mutant AML1D171N allele and activation of Evi1 via insertional mutagenesis) that converge on AML1 function.
