Figure 5
Figure 5. FACS analysis and thrombus formation in wild-type versus CD40−/− and CD40-Twt vs CD40-T6 mice. Relative amount of CD3+ T cells (A), CD4/CD8 ratio (B), and relative amounts of activated T cells (C and D showing CD25+ and CD69+ T cells, respectively) were assessed in blood, spleen and lymph nodes. Furthermore, relative amounts of circulating B cells, macrophages, and granulocytes were determined (E). Thrombocyte adhesion to collagen was measured under flow conditions. Data are percentages of surface covered with platelets after 4 minutes of perfusion (F). *P < .05 compared with wild-type. Error bars represent SEM.

FACS analysis and thrombus formation in wild-typeversus CD40−/− and CD40-Twt vs CD40-T6 mice. Relative amount of CD3+ T cells (A), CD4/CD8 ratio (B), and relative amounts of activated T cells (C and D showing CD25+ and CD69+ T cells, respectively) were assessed in blood, spleen and lymph nodes. Furthermore, relative amounts of circulating B cells, macrophages, and granulocytes were determined (E). Thrombocyte adhesion to collagen was measured under flow conditions. Data are percentages of surface covered with platelets after 4 minutes of perfusion (F). *P < .05 compared with wild-type. Error bars represent SEM.

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