Expression of decorin in donor and patient MSCs and osteoblasts, and after bortezomib treatment. MSCs generated from healthy donors (n = 3) and patients with myeloma (n = 3) were differentiated into osteoblasts (OB) in the absence or presence of bortezomib (BOR, 2 nM) for 2 weeks. Decorin expression was determined by qRT-PCR amplification. Note the increased expression of decorin after differentiation of donor and patient MSCs into osteoblasts. Decorin expression was insignificantly lower in patient than in donor MSCs and osteoblasts and higher after bortezomib treatment.