Figure 5
Figure 5. Mechanistic analysis of mitochondrial damage in CLL cells. (A) CLL cells were treated with or without 1.0 μM FP (6 hours), and mitochondrial and cytosolic fractions were isolated. (B) Mcl-1 levels in mitochondria relative to the control protein VDAC, and (C) Bcl-XL and cytochrome c in cytosolic fractions were analyzed by immunoblot. Data represent 3 independent experiments.

Mechanistic analysis of mitochondrial damage in CLL cells. (A) CLL cells were treated with or without 1.0 μM FP (6 hours), and mitochondrial and cytosolic fractions were isolated. (B) Mcl-1 levels in mitochondria relative to the control protein VDAC, and (C) Bcl-XL and cytochrome c in cytosolic fractions were analyzed by immunoblot. Data represent 3 independent experiments.

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