Figure 3
Figure 3. Levels of DC maturation markers are differentially controlled by MAPK and IRF3 pathways. Levels of DC maturation markers were estimated from 6 independent experiments by surface staining and flow cytometry. Results from 2 of the 6 independent experiments as shown in Figure 2. Mean fluorescent intensities for each marker on GFP-expressing transduced DCs are shown. Gray and black bars correspond to 2 independent experiments. Lentivectors encoding the indicated activators used for transductions are shown on the bottom of the graphs. Selected statistical comparisons between indicated samples and GFP-expressing DCs are shown, and were performed as described in “Statistical analysis”; in this case 6 independent experiments were compared by nomalizing the MFIs to the LPS value. *, significant differences (P < .05).

Levels of DC maturation markers are differentially controlled by MAPK and IRF3 pathways. Levels of DC maturation markers were estimated from 6 independent experiments by surface staining and flow cytometry. Results from 2 of the 6 independent experiments as shown in Figure 2. Mean fluorescent intensities for each marker on GFP-expressing transduced DCs are shown. Gray and black bars correspond to 2 independent experiments. Lentivectors encoding the indicated activators used for transductions are shown on the bottom of the graphs. Selected statistical comparisons between indicated samples and GFP-expressing DCs are shown, and were performed as described in “Statistical analysis”; in this case 6 independent experiments were compared by nomalizing the MFIs to the LPS value. *, significant differences (P < .05).

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