Intrafamilial correlation of IgVH usage between individuals with CLL. (A): Within sibships. (a) IgVH1-69/IgVH1-69, IgVH1-69/IgVH1-69, IgVH1-69/IgVH1-2, IgVH1-69/IgVH1-2, IgVH1-69/IgVH1-2, IgVH1-69/IgVH1-18. (b) IgVH2-5/IgVH2-5 (c) IgVH3-21/IgVH3-21, IgVH3-23/IgVH3-74, IgVH3-23/IgVH3-1, IgVH3-33/IgVH3-7, IgVH3-15/IgVH3-30, IgVH3-53/IgVH3-7, IgVH3-21/IgVH3-7, IgVH3-23/IgVH3-48, IgVH3-23/IgVH3-7, IgVH3-9/IgVH3-74, IgVH3-72/IgVH3-74. (d) IgVH4-34/IgVH4-34, IgVH4-34/IgVH4-34, IgVH4-59/IgVH4-59, IgVH4-31/IgVH4-34, IgVH4-31/IgVH4-34, IgVH4-34/IgVH4-59. (B): Within parents and offspring. (e) IgVH3-53/IgVH3-21, IgVH3-48/IgVH3-23, IgVH3-7/IgVH3-23 (f) IgVH4-34/IgVH4-b.