Histopathologic spectrum of AITL and patterns of CXCL13 expression. Panels A-E illustrate the large spectrum of angioimmunoblastic lymphoma. Panels F,G illustrate CXCL13 immunostaining patterns: (A) classic-type, (B) rich in large cells, (C) with hyperplastic germinal centers, (D) rich in clear cells, (E) rich in epithelioid cells (hematoxylin eosin stain); (F) score 1, (G) score 2, and (H) score 3. Images were captured by a Zeiss microscope (Carl Zeiss, Heidelberg, Germany); original magnifications ×25 (C) and ×250 (A,B,D-H). The different morphologic subtypes and the level of CXCL13 expression did not influence survival.