Figure 3
MYCN is up-regulated in MCL cases with t(2;14)(p24;q32). Expression of MYCN in 3 samples (LN, BM, and PE) from case 8 and LN samples from cases 5 and 7. Note up to 90-fold overexpression of MYCN in the analyzed samples from case 8 and case 7 with t(2,14)(p24;q32)/IGH-MYCN. The negative controls and the LN sample from case 5 did not exceed the threshold level (black line) of 1.6. The neuroblastoma case that was used as positive control showed up to 180-fold overexpression of MYCN mRNA. The qRT-PCR data are representative of three independent experiments. Measurements were performed in triplicate and results are means (± SEM).

MYCN is up-regulated in MCL cases with t(2;14)(p24;q32). Expression of MYCN in 3 samples (LN, BM, and PE) from case 8 and LN samples from cases 5 and 7. Note up to 90-fold overexpression of MYCN in the analyzed samples from case 8 and case 7 with t(2,14)(p24;q32)/IGH-MYCN. The negative controls and the LN sample from case 5 did not exceed the threshold level (black line) of 1.6. The neuroblastoma case that was used as positive control showed up to 180-fold overexpression of MYCN mRNA. The qRT-PCR data are representative of three independent experiments. Measurements were performed in triplicate and results are means (± SEM).

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