6-gene model predicts OS and PFS in patients with DLBCL treated with R-CHOP chemotherapy. Kaplan-Meier curves of OS (A) and PFS (B) in 132 patients with DLBCL show that low-risk patients, as defined by the 6-gene model, exhibit significantly longer OS (P = .002) and PFS (P = .038). For the model based on a continuous variable, P = .002 for OS and P = .010 for PFS. PFS data are missing for 3 patients.