Figure 1
![Figure 1. Toxicity profiles of gossypol versus apogossypol in normal mice. Female Balb/c mice (7 weeks old) (n = 6 per group) were orally administered vehicle control (■), 120 μmol/kg gossypol (•), or 120 μmol/kg apogossypol (♦) 5 times weekly for 3 weeks. (A) Percentage survival of mice is shown over time. (B) Body weight is shown over time, in grams (mean ± standard deviation [SD]). Data are representative of several experiments involving a total of 20 gossypol-treated, 40 apogossypol-treated, and 20 vehicle control–treated mice.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/111/6/10.1182_blood-2007-09-113647/6/zh80060817090001.jpeg?Expires=1722718525&Signature=qrDJCuTsE381QGukzB1jqJk1krOIfCQv0ktBd1GMvOgO7dpsxSdPuF~8dkux11b7uZVt2B~LHWtzRejhVxDfqwdE-EFQ4UnjTkvPM1Csw0CV5FLeGSBtI0UjDdpM5eK9nSU1Fx-LfCDwrrl7ToTNHkfEuyFRE4sJSui38Ttv0cIRQJuNnTkbOTN3nJ-q3HOSmOIO3YlJ4~TDroPFLozmjc20LP2pT1F7R5ZczXINxm9znPXVEI3Pg0NQIlkLZjHj7SZSv8lZdz9Hxjj1nVDkFxItJ~kFIxCmt3ak5Gt6yG~4cNncoPWPZ9qFj8SxZIZPIDXEReHL9qRaWWriv~ShEA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Toxicity profiles of gossypol versus apogossypol in normal mice. Female Balb/c mice (7 weeks old) (n = 6 per group) were orally administered vehicle control (■), 120 μmol/kg gossypol (•), or 120 μmol/kg apogossypol (♦) 5 times weekly for 3 weeks. (A) Percentage survival of mice is shown over time. (B) Body weight is shown over time, in grams (mean ± standard deviation [SD]). Data are representative of several experiments involving a total of 20 gossypol-treated, 40 apogossypol-treated, and 20 vehicle control–treated mice.
