Figure 2
Whole genome association scans performed with pooled DNA generated based on immunophenotyping with CTL-2A12. Pooled DNAs generated from 44 CTX+ and 44 CTX− B-LCLs were analyzed with 50 K XbaI (A), 50 K HindIII (B), 250 K NspI (C), and 250 K StyI (D) arrays. Test statistics were calculated for all SNPs and plotted in the chromosomal order. In all SNP array types, a common association peak is observed at 18q21, to which the minor H antigen for CTL-2A12, encoded by the HMSD gene, had been mapped based on expression cloning9 (arrows).
