Figure 2
Figure 2. Analysis of adoptively transferred monocyte migration to the dermis and PO-LNs during Leishmania major infection. (A) Experimental model for the analysis of adoptively transferred monocyte migration. (B) Identification of adoptively transferred Ly-5.1+ monocytes and mo-DCs at 3 weeks after infection. (C-F) Effect of treatment with mAbs against rolling molecules on the absolute number of monocytes in the dermis (C), monocytes in the PO-LNs (D), dermal mo-DCs after migration to the PO-LNs (E), and LN mo-DCs (F). (G) Proposed model for the differential participation of PSGL-1 and L-selectin on monocyte transendothelial migration through inflamed DVs and HEVs. Data are representative of 3 independent experiments with similar results.

Analysis of adoptively transferred monocyte migration to the dermis and PO-LNs during Leishmania major infection. (A) Experimental model for the analysis of adoptively transferred monocyte migration. (B) Identification of adoptively transferred Ly-5.1+ monocytes and mo-DCs at 3 weeks after infection. (C-F) Effect of treatment with mAbs against rolling molecules on the absolute number of monocytes in the dermis (C), monocytes in the PO-LNs (D), dermal mo-DCs after migration to the PO-LNs (E), and LN mo-DCs (F). (G) Proposed model for the differential participation of PSGL-1 and L-selectin on monocyte transendothelial migration through inflamed DVs and HEVs. Data are representative of 3 independent experiments with similar results.

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