Nonrestoration of NCR surface expression on patients in therapeutic failure or relapse. (A) NK cells from patients in therapeutic failure were analyzed for NKp46 (○) or NKp30 (♦) surface expression. Y-axis represents MFI of PE-conjugated mAbs. X-axis represents number of days after diagnosis (D0). (B) NK cells from patients in relapse. NKp46 (left panel) and NKp30 (right panel) were analyzed on NK cells of AML patients at CR (▪) and after relapse (□). Data represent MFI of PE-conjugated mAb staining for 3 of 4 patients in relapse. Dashed lines correspond to mean of NKp30 expression by NK cells from 23 healthy donors. Solid horizontal lines correspond to mean of NKp46 expression by NK cells from 23 healthy donors.