DDR1 activation and NF-κB activation in the eosinophils of CSS patients. (A) Western blot analysis for phospholyrated DDR1 and Shc by the stimulation with DDR1 agonistic antibody, control IgM, and collagen. (B) Western blot analysis for Flag fusion protein with or without collagen-binding site of DDR1. (C) Analysis of nuclear NF-κB translocation in the eosinophils of CSS patients by the stimulation with DDR1 agonistic antibody, control IgM, and collagen in the presence or absence of β1 integrin–neutralizing antibody, DDR1-blocking protein, and control protein. (D) Comparison of NF-κB density (*P < .001, Bonferroni-Dunn test with 1-way factorial ANOVA). Error bars indicate standard deviation.