Different T-cell reconstitution patterns prior to DLIs. Flow cytometry analyses were performed on CD4 T cells (median, -○-; range, dotted line) and CD8 T cells (median, -•-; range, solid line) of peripheral blood samples. (A) Early reconstitution pattern in 7 patients who all developed persistent grade I aGVHD and, therefore, did not receive subsequent DLI therapy. (B) Failure to reconstitute circulating T cells in 9 patients who did not develop spontaneous GVHD and received CD8-depleted DLIs later on.