Figure 5
![Figure 5. CsA increases the concentrations of INNO-406 in the CNS. Radioactivity (A) and concentration (B) of INNO-406 in the brains of mice that had been orally administered 30 mg [14C]INNO-406/kg with (○) or without (•) prior administration of 50 mg CsA/kg. Radioactivity (C) and concentration (D) of INNO-406 in the plasma of mice that had been orally administered 30 mg [14C]INNO-406/kg with (○) or without (•) 50 mg CsA/kg. Error bars indicate standard deviation.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/109/1/10.1182_blood-2006-03-013250/4/zh80010706040005.jpeg?Expires=1723469469&Signature=HKMjkDF73fMmWj7LLrlhcJ9~bVPvy0o52Fu4I11t9T8SUncjdgtRggMOeEFdSusi1DaRgJDvDI4WqHpCRWl0e1VYIgGrzNvkkhtvAo-bSYx2JnPwQooCl7mxr2kcsUSYz~79~WtkVv4mREqNFwmF-6Vs48QLh4NCUd6UAR178yjSJC8zWWiF9eqe0JJTOJhGxhrs9OnetDP8NnXG9gKxXOWuapdGDjjBlv8aw6xj6kPTaH3l2E6aoU-V6ompwH0YxFfEQJ4zN0KWeSSAbdu7V4A8I~nq~jLloOp99LzSnn6mfaLBHrmkrI86ZA4irnF9iQP5WTZGbDoZeFGWk3IDdA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CsA increases the concentrations of INNO-406 in the CNS. Radioactivity (A) and concentration (B) of INNO-406 in the brains of mice that had been orally administered 30 mg [14C]INNO-406/kg with (○) or without (•) prior administration of 50 mg CsA/kg. Radioactivity (C) and concentration (D) of INNO-406 in the plasma of mice that had been orally administered 30 mg [14C]INNO-406/kg with (○) or without (•) 50 mg CsA/kg. Error bars indicate standard deviation.
