Rupture force spectra demonstrating the interactions of desB-fibrin with fragment D from normal fibrinogen and fragment DD from cross-linked fibrin in the absence and presence of specific inhibitors of B:b and B:a interactions. (A) Interactions between desB-fibrin and fragment D. (B) The same interactions in the presence of 2 mM GPRPam, the specific inhibitor of potential B:a binding. (C) Interactions between desB-fibrin with fragment DD. (D-F) Complete inhibition of the interactions between desB-fibrin and fragment D by the mAb T2G1 against the β15-21 portion of fibrin, by 10 mM GHRPam, and by the free soluble recombinant fragment (β15-66)₂, respectively.