Histologic and immunophenotypical correlation with cluster. Representative biopsies are shown. Left panels are the hematoxylin-eosin stain, and right panels are immunohistochemical stains using monoclonal antibody to CD3. (A) Cluster 2: stage IA, untreated erythematous plaque on the chest. (B) Cluster 3: top 2 panels depict a stage IB lesion, while the bottom panel shows a stage III lesion. All images were acquired on a Nikon Eclipse E600 microscope (Nikon, Melville, NY) with a 10×/0.30 objective using a SPOT digital camera and image acquisition software (Diagnostic Instruments, Sterling Heights, MI).