IL-6 and iNOS expression is increased in LRP-1–deficient cells. (A) PEA-10 and MEF-2 cells were grown for 18 hours in SFM. Expression of IL-6 and iNOS was analyzed by qPCR. (B) RAW 264.7 cells were transiently transfected with NTC or LRP-1–specific siRNA. Expression of iNOS was analyzed by qPCR 36 hours after transfection. Error bars represent SD.