Figure 2
Figure 2. TSLP Tg expression restores splenic lymphocyte compartments in IL-7−/− mice. (A) Absolute splenocyte numbers of IL-7−/−, WT, and IL-7−/− K14-TSLP Tg (12-week-old). (B) Percentages and (C) absolute cell number of CD4+, CD8+, and γδ+CD3+ T cells, and CD19+CD93− mature B cells composed of follicular (CD23+ CD21+) and MZ (CD21high CD23−) B cells are shown. Histograms represent the mean and standard deviation from analyzing 5 animals. *P < .05; **P < .005 (Student t test). (D) Gated on splenic CD4+ and CD8+ T cells, CD62L and CD44 expression is shown.

TSLP Tg expression restores splenic lymphocyte compartments in IL-7−/− mice. (A) Absolute splenocyte numbers of IL-7−/−, WT, and IL-7−/− K14-TSLP Tg (12-week-old). (B) Percentages and (C) absolute cell number of CD4+, CD8+, and γδ+CD3+ T cells, and CD19+CD93 mature B cells composed of follicular (CD23+ CD21+) and MZ (CD21high CD23) B cells are shown. Histograms represent the mean and standard deviation from analyzing 5 animals. *P < .05; **P < .005 (Student t test). (D) Gated on splenic CD4+ and CD8+ T cells, CD62L and CD44 expression is shown.

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