Figure 5
Figure 5. A genome-wide representation of DC subsets of myeloid or lymphoid origin by microarray analysis. (A) Scatter plots of signal intensity of 48 000 different transcripts measured on an Illumina beads chip microarray. Data are presented as CMP- versus CLP-derived pDCs (i), CMP- versus CLP-derived cDCs (ii), CMP-derived cDCs versus pDCs (iii), and CLP-derived cDCs versus pDCs (iv). Representative data of 3 independent experiments are shown. (B) The heat map representation of 218 genes that displayed more than 3-fold differences between cDCs and pDCs of each lineage origin. The expression pattern of these genes is well preserved in each DC subset irrespective of its CMP or CLP origin. Representative data of 3 independent experiments are shown. L and M denote lymphoid and myeloid origin, respectively.

A genome-wide representation of DC subsets of myeloid or lymphoid origin by microarray analysis. (A) Scatter plots of signal intensity of 48 000 different transcripts measured on an Illumina beads chip microarray. Data are presented as CMP- versus CLP-derived pDCs (i), CMP- versus CLP-derived cDCs (ii), CMP-derived cDCs versus pDCs (iii), and CLP-derived cDCs versus pDCs (iv). Representative data of 3 independent experiments are shown. (B) The heat map representation of 218 genes that displayed more than 3-fold differences between cDCs and pDCs of each lineage origin. The expression pattern of these genes is well preserved in each DC subset irrespective of its CMP or CLP origin. Representative data of 3 independent experiments are shown. L and M denote lymphoid and myeloid origin, respectively.

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