Actions of RPS19. The illustration summarizes the known functions and interactions of RPS19. RPS19 is reported to interact with PIM-1, Nep1p, S19BP, FGF-2, and eIF-2α, as well as being phosphorylated in vitro. RPS19 is required for 18S rRNA and 40S subunit maturation. Most of the suggested functions of the RPS19 protein are within the translational machinery.