All samples assigned to TC subtypes based on expression of D cyclins and translocation target genes (n = 264). (A) The TC subtypes of 264 relapsed myeloma samples are shown. The y-axis shows normalized expression level of each gene; subtypes were determined as in Bergsagel et al.33 (B) A comparison of the TC subtype frequency for relapsed patients in Millennium Pharmaceuticals (MPI) studies (green) and for newly diagnosed patients (blue) as defined at the University of Arkansas.33