Figure 1
![Figure 1. DL1 signaling enhances B-cell proliferation after BCR stimulation. (A) Histogram presents 3[H]-thymidine uptake by CD23+ splenic B cells (FO B cells) stimulated with anti-IgM for 72 hours. Error bars represent standard error of the mean (SEM) (n = 9). (B) FO B cells were labeled with CFSE and cultured for 72 hours on OP9-DL1 (solid lines) or OP9-Ctrl (dashed lines) cultures with the indicated amounts of anti-IgM and without or with GSI (γ-secretase inhibitor). Results are representative of 5 independent experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/109/8/10.1182_blood-2006-09-046698/4/zh80080711350001.jpeg?Expires=1724243752&Signature=XrDdh9Em7TZm6TGLrn3BkBEKvcrg3v8-peLBecUmqGisIWSqPSCJAus9Gk35cBwv~cC0ieixHo8TiIu-Hao82JEpE4dE056s8kwJJG-O7RzMPLtiY9Qwg4u-2DT70K~fXpddDzzac7CXsDHHohwKx~KBzzXIc1WcxeoaZ2vTfImRK8VwntK9u3Ms1j8hT2EC0DImrjn5EwdxrPXXxwOnER9KyiQXMuAoQjoOybv3L6bXZa0LMR8F9hVJ4gB3oq9M6bq0aSRIRKSFkDBKPk8APfsUyLaViSF6JT9yy7CGLKAnT4qohbzJPMTRkOY45P~aabMtFrlTOs1G97-8MwgBfA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
DL1 signaling enhances B-cell proliferation after BCR stimulation. (A) Histogram presents 3[H]-thymidine uptake by CD23+ splenic B cells (FO B cells) stimulated with anti-IgM for 72 hours. Error bars represent standard error of the mean (SEM) (n = 9). (B) FO B cells were labeled with CFSE and cultured for 72 hours on OP9-DL1 (solid lines) or OP9-Ctrl (dashed lines) cultures with the indicated amounts of anti-IgM and without or with GSI (γ-secretase inhibitor). Results are representative of 5 independent experiments.
