Figure 4.
![The effect of expression of dominant-negative RhoA on proliferation and cell-cycle progression. (A) [3H] Thymidine uptake of ckit+ cells expressing dominant-negative RhoA; control (▪), RhoAN19 (□). Data represent the mean ± SEM of 3 independent experiments, *P < .01 versus control group. (B-E) Flow cytometric analysis of cell-cycle status of transduced ckit+ cells. (B-C) Cells expressing the control virus. (D-E) Cells expressing RhoAN19. (C,E) Cells stimulated with SCF for 9 hours. The percentage of cells in each phase of cell cycle is shown at upper right. Data are representative of 4 independent experiments. *P < .05 versus control group.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/108/6/10.1182_blood-2006-02-001560/4/zh80180601410004.jpeg?Expires=1721562204&Signature=Q-tASZpbB5PDZX0mB97HI3tTCCNLxM3mHs93vVSDf7AJriIMMn6EOuldkhZZLOCGOPPg9LUjlr7wmPd-5hr1XHZUeR04gWowy2A8bDJFVSnkbCtAXZ0SHs7uH3coksOAFM37WPMKYdMgtHvjwVMZ0Ny3eiicXMkRSgk-bxIDk~C-cigeEzek3hQQxx9xjg0lc-m-Z22aPKSPgSXIbaXO3MgaKJoGq5~sWIl8dytR8znPL0TucxnzhtuDyRtw0IFfEopdN5Dxy3RO43M0AhL25ZAi4ZCI~TKAQZi5WX8Zegs2qSly1sBzWK1p0SSGhanmVL2SMrn~WYr6S7e9aMEBKg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
The effect of expression of dominant-negative RhoA on proliferation and cell-cycle progression. (A) [3H] Thymidine uptake of ckit+ cells expressing dominant-negative RhoA; control (▪), RhoAN19 (□). Data represent the mean ± SEM of 3 independent experiments, *P < .01 versus control group. (B-E) Flow cytometric analysis of cell-cycle status of transduced ckit+ cells. (B-C) Cells expressing the control virus. (D-E) Cells expressing RhoAN19. (C,E) Cells stimulated with SCF for 9 hours. The percentage of cells in each phase of cell cycle is shown at upper right. Data are representative of 4 independent experiments. *P < .05 versus control group.
