Hematologic and molecular response to AZT and IFN-α in ATLL patients. (A, left) WBC counts were plotted over time for 2 ATLL patients with leukemia after induction and during antiviral treatment. (B, right) Analysis of T-cell clones is demonstrated by combined multiplex PCR at the specified dates for these 2 patients using two sets of reaction primers, including those specific to the V_1-8, V₉, and consensus J₁ and J₂ regions of βchain TCR genes (peaks to the right) or alternative J₁ and J₂ regions (peaks to the left).