Expression of negative prognostic markers by homHCDR3–IGHV3-21 and nonhomHCDR3–IGHV3-21 CLLs. (A) The plot represents CD38, CD49d, CD79b, and ZAP-70 expression values in 8 homHCDR3–IGHV3-21 (▪) and 6 nonhomHCDR3–IGHV3-21 (□) CLLs. The horizontal line corresponds to the cutoff value of 30% of positive cells. The χ2 test reported on the right compares the number of cases (homHCDR3–IGHV3-21 or nonhomHCDR3–IGHV3-21 CLLs) in which the expression of each phenotypic marker was expressed above or below the 30% of positive cells threshold. (B) Grids indicating the expression of the 4 prognostic markers CD38, CD49d, CD79b, and ZAP-70 in the 6 nonhomHCDR3–IGHV3-21 (left grid) and in the 8 homHCDR3–IGHV3-21 (right grid) CLLs. Black or white boxes indicate expression of the marker above or below the 30% cutoff, respectively. Gray boxes indicate no data are available.
