IgG-mediated clearance of incompatible hGPA-Tg-mRBCs: time-course studies. Wild-type FVB/NJ mice were passively immunized intraperitoneally with 500 μg of the purified 10F7 anti–hGPA IgG1 mAb (A) or with 50 μg of the purified NaM10-2H12 anti–hGPA IgG3 mAb (B). Sixteen hours later they were transfused with ⁵¹Cr-labeled hGPA-Tg-mRBCs, and then RBC survival was quantified at the indicated time points. The number of mice evaluated at each time point is indicated in parentheses; the mean ± 1 SD is provided for each time point.