Relative levels of expression of bcl2 hnRNA and bcl2 mRNA in stable clones of MCF-7 cells. The levels of bcl2 hnRNA and bcl2 mRNA in MCF-7 cells transfected with either a scrambled siRNA (□) or a nucleolin siRNA (▪) and (▒) were determined by real-time quantitative PCR. Results are expressed as the means of 4 determinations per group ± SEM. *P < .001 compared with either of the nucleolin siRNA transfected clones.