Restored formation of nuclear Rad51 foci in FA-D1 mouse fibroblasts transduced with LVs expressing hBRCA2. (A) Description of the LVs harboring the hBRCA2 (BRCA2-LV) and EGFP cDNA (EGFP-LV) used throughout. (B) Percentages of mouse FA-D1 fibroblasts with Rad51 foci after 20 hours of incubation in the presence or absence of 30 nM MMC. Data are mean plus or minus SEM of 3 independent experiments. A total of 200 cells were scored in each condition. (C) Representative immunofluorescence pictures corresponding to analysis shown in panel B. *Significant difference (P < .05). N.S. indicates not significant.