Survival of humanized NOD-SCID mice in a model of active EBV infection. Kaplan-Meier survival curve of NOD-SCID mice in an active infection model. Mice reconstituted with PDC-enriched (extra 1 × 10⁵ autologous PDCs) PBMCs (1 × 10⁸) from IgG⁺ human blood donors with EBV (n = 8, •) had significantly delayed mortality from EBV-associated lymphoma compared to mice reconstituted with PBMCs and EBV (n = 8, □) or IFN-α-pulsed PBMC and EBV (n = 8, ▵; log-rank P = .004). Two mice in the PDC-enriched PBMC group had no evidence of EBV lymphoma (*).