Figure 4
Enzastaurin induces MM-cell apoptosis. (A) Dose-related effects of enzastaurin on survival of MM cell lines and healthy donors. PBMC indicates peripheral blood mononuclear cell. MTT cleavage was measured during the last 4 hours of 48-hour cultures. (B) Protein profiling of MM cells exposed to enzastaurin. MM.1S cells were exposed to increasing concentrations of enzastaurin, followed by immunoblot analysis of the lysates with indicated antibodies.

Enzastaurin induces MM-cell apoptosis. (A) Dose-related effects of enzastaurin on survival of MM cell lines and healthy donors. PBMC indicates peripheral blood mononuclear cell. MTT cleavage was measured during the last 4 hours of 48-hour cultures. (B) Protein profiling of MM cells exposed to enzastaurin. MM.1S cells were exposed to increasing concentrations of enzastaurin, followed by immunoblot analysis of the lysates with indicated antibodies.

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