Figure 4
Figure 4. Splenic areas and VCAM-1 expression after adoptive transfer. (A) Areas of splenic white pulps, B cells, and T cells. White pulp area (i), B-cell area (ii), and T-cell area (iii) in LTα−/− mice that were adoptively transferred with normal splenocytes, CD11c+ DCs and pDCs, adult CD4+CD3− cells, or E15 CD4+CD3− cells compared with normal white pulp areas. Bar shows mean values with high and low values calculated from 10 different white pulp areas. (B) VCAM-1 expression after adoptive transfer. Statistical differences were calculated using a nonparametric Mann-Whitney test. *Statistical significance by Mann-Whitney P ≤ .05; **P ≤ .005. Results representative of at least 2 experiments

Splenic areas and VCAM-1 expression after adoptive transfer. (A) Areas of splenic white pulps, B cells, and T cells. White pulp area (i), B-cell area (ii), and T-cell area (iii) in LTα−/− mice that were adoptively transferred with normal splenocytes, CD11c+ DCs and pDCs, adult CD4+CD3 cells, or E15 CD4+CD3 cells compared with normal white pulp areas. Bar shows mean values with high and low values calculated from 10 different white pulp areas. (B) VCAM-1 expression after adoptive transfer. Statistical differences were calculated using a nonparametric Mann-Whitney test. *Statistical significance by Mann-Whitney P ≤ .05; **P ≤ .005. Results representative of at least 2 experiments

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