Marrow MRD evolution according to early response. Individual RQ-PCR MRD monitoring is shown for good (corticosensitive and chemosensitive) and poor (corticoresistant and/or chemoresistant) early responders, respectively. Not surprisingly, the rate of PCR negativity was higher after HAMI in good early responders than after DIV in poor early responders (57% versus 17%; P = .01).