Figure 1
Figure 1. Liver ferrochelatase activity and erythrocyte PPIX levels in wild-type and fch/fch mice of 3 congenic strains. (A) Liver FECH activity in wild-type (▪) and fch/fch female (○) mice measured as zinc chelatase (nmol zinc protoporphyrin [Zn-PPIX]/h per milligram protein). Differences between FECH activity across strains in wild-type mice were not statistically different. (B) Free-erythrocyte PPIX level measured in nanomolar. Data are expressed as mean ± SD of 6 mice per genotype. **Significance of the influence of the fech mutation on each parameter (P < .001).

Liver ferrochelatase activity and erythrocyte PPIX levels in wild-type and fch/fch mice of 3 congenic strains. (A) Liver FECH activity in wild-type (▪) and fch/fch female (○) mice measured as zinc chelatase (nmol zinc protoporphyrin [Zn-PPIX]/h per milligram protein). Differences between FECH activity across strains in wild-type mice were not statistically different. (B) Free-erythrocyte PPIX level measured in nanomolar. Data are expressed as mean ± SD of 6 mice per genotype. **Significance of the influence of the fech mutation on each parameter (P < .001).

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