Figure 4.
Figure 4. Impaired antibody response during a chronic viral infection in SAP– mice. Serum antibody levels were determined by quantitative ELISA at day 30 of chronic LCMVcl13 infection. (A) Anti-LCMV serum IgG concentration was 12-fold higher in WT than in SAP– mice (P < .007) (WT, n = 13; SAP–, n = 4). Data are representative of 3 independent experiments. (B) Total serum IgG concentration was 9-fold higher in WT than in SAP– mice (P < .003).

Impaired antibody response during a chronic viral infection in SAP– mice. Serum antibody levels were determined by quantitative ELISA at day 30 of chronic LCMVcl13 infection. (A) Anti-LCMV serum IgG concentration was 12-fold higher in WT than in SAP– mice (P < .007) (WT, n = 13; SAP–, n = 4). Data are representative of 3 independent experiments. (B) Total serum IgG concentration was 9-fold higher in WT than in SAP– mice (P < .003).

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