Enhanced induction of antitumor effect by immunization with DIgR2-siRNA-DCs. C57BL/6 mice (n = 5 mice/group) mice were preimmunized twice at weekly intervals with 1 × 10⁶ of OVA-pulsed, transduced, or mock DCs with ex vivo maturation. Seven days after the final immunization, OVA⁺ EG7 tumor cells (2 × 10⁶) were inoculated subcutaneously. Tumor size (A) and percentage of mice with tumor (B) were monitored twice a week. The data represent 1 of 2 independent experiments. Error bars indicate SE.