Figure 5.
Figure 5. Increased cytarabine resistance of clonogenic progenitors (CFU-Cs) following CDD gene transfer. Bone marrow harvested at the end of experiment C3 from 4 animals (2 each given transplants with CDD or control-transduced grafts) were exposed to increasing concentrations of cytarabine in clonogenic cultures. Drug resistance was assessed in triplicate cultures per animal and drug concentration.

Increased cytarabine resistance of clonogenic progenitors (CFU-Cs) following CDD gene transfer. Bone marrow harvested at the end of experiment C3 from 4 animals (2 each given transplants with CDD or control-transduced grafts) were exposed to increasing concentrations of cytarabine in clonogenic cultures. Drug resistance was assessed in triplicate cultures per animal and drug concentration.

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