Mutated BCR-ABL clone kinetics. The figure shows BCR-ABL transcript levels as measured by RQ-PCR and the relative size of the mutant clone while the patients were being treated with IM as single agent. The black and red lines represent the total BCR-ABL transcripts and the percentage of the mutant clone, respectively. The horizontal arrows represent the duration of the IM treatment. The IM dose is indicated in milligrams per day.