Hepatic fibrosis in response to S mansoni infection. (A) Picrosirius red staining of fibrous tissue in granulomata of wild-type BALB/c and eosinophil lineage–ablated ΔdblGATA mice at week 8 of infection. (B) Differential expression of transcripts encoding collagen I, collagen III, and collagen VI in liver RNA from uninfected and S mansoni–infected BALB/c and ΔdblGATA mice. Values are mean fold change ± SEM with expression in uninfected BALB/c mice normalized to 1.0.