Figure 2.
Figure 2. Characterization of the chromosomal junctions of the BCL6 translocations in gastric lymphoma. (A) Nucleotide sequences of the chromosomal junctions and breakpoints of Ig/BCL6 translocations. The overlapping nucleotides of the junction sequences of BCL6 and the fusion partners are doubly underlined. Variable numbers of nucleotides of unknown origin inserted at the breakpoints are shown in lowercase letters and are not underlined. The number within each bracket indicates the distance between the 2 nucleotides. (B) Schematic representation of the non-Ig/BCL6 translocations. ▪ and □ represent exons from BCL6 and the fusion partners, respectively. Vertical arrows indicate the chromosomal junctions and breakpoints of non-Ig/BCL6 fusion genes. The overlapping nucleotides of the junction sequences of BCL6 and the fusion partner genes are underlined. Open arrowheads indicate coding initiation start sites. *DLCLML cases.

Characterization of the chromosomal junctions of the BCL6 translocations in gastric lymphoma. (A) Nucleotide sequences of the chromosomal junctions and breakpoints of Ig/BCL6 translocations. The overlapping nucleotides of the junction sequences of BCL6 and the fusion partners are doubly underlined. Variable numbers of nucleotides of unknown origin inserted at the breakpoints are shown in lowercase letters and are not underlined. The number within each bracket indicates the distance between the 2 nucleotides. (B) Schematic representation of the non-Ig/BCL6 translocations. ▪ and □ represent exons from BCL6 and the fusion partners, respectively. Vertical arrows indicate the chromosomal junctions and breakpoints of non-Ig/BCL6 fusion genes. The overlapping nucleotides of the junction sequences of BCL6 and the fusion partner genes are underlined. Open arrowheads indicate coding initiation start sites. *DLCLML cases.

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