Figure 4.
Figure 4. CD11bhiIalo DCs inhibit allo-DTH in vivo. B6 mice were immunized on the dorsal flank by subcutaneous inoculation of BALB/c spleen cells (1 × 107/mouse) on day 0, and challenged on day 7 and day 14 at the hind footpad by injecting the same antigens (1 × 107/mouse). APCs were injected intraperitoneally (3 × 106/mouse) on days –6, –4, 0, 3, and 6. Footpad thickness was then measured on day 8 and day 15 with a calipers-type engineer's micrometer by a third experimenter who did not know the sample identity. Data are representative of 2 independent experiments, showing the means ± SDs of footpad swelling on indicated day. *P < .05, **P < .01.

CD11bhiIalo DCs inhibit allo-DTH in vivo. B6 mice were immunized on the dorsal flank by subcutaneous inoculation of BALB/c spleen cells (1 × 107/mouse) on day 0, and challenged on day 7 and day 14 at the hind footpad by injecting the same antigens (1 × 107/mouse). APCs were injected intraperitoneally (3 × 106/mouse) on days –6, –4, 0, 3, and 6. Footpad thickness was then measured on day 8 and day 15 with a calipers-type engineer's micrometer by a third experimenter who did not know the sample identity. Data are representative of 2 independent experiments, showing the means ± SDs of footpad swelling on indicated day. *P < .05, **P < .01.

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